Many endodontic procedures are performed to relieve the pain of toothaches caused by pulp inflammation or infection. With modern techniques and anesthetics, most patients report that they are comfortable during the procedure. For the first few days after treatment, your tooth may feel sensitive, especially if there was pain or infection before the procedure. Your tooth may also continue to feel slightly different from your other teeth for some time after your endodontic treatment is completed. This discomfort can be relieved with over-the-counter or prescription medications. Follow your endodontist’s instructions carefully. However, if you have severe pain or pressure or pain that lasts more than a few days, call your endodontist.